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| Pyruvic acid is a component of the human body. It mainly participates in the metabolism of sugar, fat, etc. in the human body. It is also one of the intermediate products of carbohydrate metabolism. Pyruvic acid is also called acetoformic acid, pyrogluconic acid, and 2-oxopropionic acid. It is a light yellow to yellow transparent liquid. It has an acetic acid smell. It has a sour taste. Natural products exist in mint and sucrose fermentation broth. Relative molecular mass 88.06. Relative density 1.2271. Melting point 13.8℃. Boiling point 165℃ (decomposition), 106.5℃ (13.332×103Pa), 85.3℃ (5.333×103Pa), 70.8℃ (2.666×103Pa), 57.9℃ (1.333×103Pa), 45.8℃ (0.667×103Pa), 21.4℃ (0.133×103Pa). Flash point 82℃. Refractive index 1.4280. Miscible with water, ethanol, ether, etc. Darkens in air. Slowly polymerizes when heated, highly reactive, easily reacts with nitrides, aldehydes, halides, phosphides, etc., and participates in the biochemical synthesis, metabolism, alcohol fermentation, etc. of sugar metabolism, colloids, amino acids, proteins, etc. in organisms. When exerting force, it is reduced to lactic acid in muscles, and is oxidized again and partially converted into glycogen when resting. Rat oral LD502100mg/kg. Uses: It is used in the synthesis of medicines, amino acids (substrates of L-tyrosine), etc., which can improve efficiency, especially in the pharmaceutical industry, where it can shorten and simplify the process. For example, 2-phenylcinchonic acid made from this product is an antipyretic, analgesic and diuretic. Using this product as a raw material can greatly reduce production costs. In addition, it is also used as a raw material for the synthesis of anti-tuberculosis drugs, calcium isoniazid pyruvate, hormones, and the anthelmintic pyruniumpamote. It is also used as a raw material for pesticides. Using pyruvic acid, indole and ammonia as raw materials, biochemical reactions can produce tryptophan. In the production of monosodium glutamate, this product can be used to increase the yield of L-threonine. Spices are edible spices allowed for use in accordance with my country's GB2760-1996 regulations. Preparation method: 1. Use lactic acid ester as a raw material to obtain acetone ester by gas phase or liquid phase oxidation, and further hydrolysis can be used to obtain acetone ester. 2. Take tartaric acid as raw material, add potassium bisulfate and sodium bisulfate, heat to 210-220℃, dehydrogenate, and get crude pyruvic acid, which can be refined by vacuum distillation. 3. Take 2,2-dichloropropionic acid as raw material, use sodium hydroxide, adjust pH to about 6, and hydrolyze to get it. | |||||||||
127-17-3
bosschemical
127-17-3
| Pyruvic acid Basic information | |
| Uses Antioxidant effect | |
| Product Name: | Pyruvic acid |
| CAS: | 127-17-3 |
| MF: | C3H4O3 |
| MW: | 88.06 |
| EINECS: | 204-824-3 |
| Mol File: | 127-17-3.mol |
| Pyruvic acid Chemical Properties | |
| Melting point | 11-12 °C (lit.) |
| Boiling point | 165 °C (lit.) |
| density | 1.267 g/mL at 25 °C (lit.) |
| vapor pressure | 1.72hPa at 25℃ |
| refractive index | n20/D 1.428(lit.) |
| FEMA | 2970 | PYRUVIC ACID |
| Fp | 183 °F |
| storage temp. | 2-8°C |
| solubility | Miscible with chloroform and methanol. |
| pka | 2.39(at 25℃) |
| form | Liquid |
| color | Clear colorless to light yellow or amber |
| Odor | at 1.00 % in propylene glycol. sharp sour acetic caramellic |
| PH | 3.11(1 mM solution);2.38(10 mM solution);1.79(100 mM solution); |
| Odor Type | acidic |
| biological source | synthetic |
| Water Solubility | H2O: miscible |
| alcohol: miscible | |
| diethyl ether: miscible | |
| Merck | 148,021 |
| JECFA Number | 936 |
| BRN | 506211 |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, strong bases. Refrigerate. |
| InChIKey | LCTONWCANYUPML-UHFFFAOYSA-N |
| LogP | -1.24 |
| Dissociation constant | 2.49 at 25℃ |
| CAS DataBase Reference | 127-17-3(CAS DataBase Reference) |
| NIST Chemistry Reference | Pyruvic acid(127-17-3) |
| EPA Substance Registry System | Propanoic acid, 2-oxo- (127-17-3) |
检验项目(Item) | 指标(Specification) | 结果(Result) |
香气描述(Odor) | 具有醋酸气味 Acetic acid odor | 合格 Pass |
外观(Appearance) | 淡黄色至黄色的透明液体 Light yellow to yellow transparent | 合格 Pass |
熔点（Physics℃) | liquid 13.8℃ | 13.8℃ |
相对密度 (Relative Density ,25/25℃) | 1.22700～1.2273 | 1.2271 |
含量(Assay by GLC,area%) | ＞98.0% | 98.5﹪ |
