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| Lactulose, also known as lactulose, isomerized lactose, 4-O-β-D-galactopyranosyl-D-fructose, etc., is a disaccharide composed of D-galactosyl and D-fructose groups linked by a β-1,4-glycosidic bond. Its molecular formula is C12H22O11, and its molecular weight is approximately 342.3. Finished lactulose is a pale yellow, transparent, viscous syrup; crystalline form is a white powder. It has higher water solubility, alcohol solubility, stability under acid and heat conditions, and sweetness than lactose. Its melting point is 169℃. | |||||||||
4618-18-2
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4618-18-2
Lactulose Basic information | |
Product Name: | Lactulose |
CAS: | 4618-18-2 |
MF: | C12H22O11 |
MW: | 342.3 |
EINECS: | 225-027-7 |
Mol File: | 4618-18-2.mol |
Lactulose Chemical Properties | |
Melting point | ~169 °C (dec.) |
Boiling point | 397.76°C (rough estimate) |
alpha | -47 º (C=5, H2O, 12HR) |
density | 1,32g/cm |
refractive index | 1,45-1,47 |
storage temp. | Refrigerator |
solubility | Freely soluble in water, sparingly soluble in methanol, practically insoluble in toluene. |
pka | 11.67±0.20(Predicted) |
form | Powder |
color | White to almost white |
Optical Rotation | [α]20/D 48±2°, 24 hr, c = 1% in H2O |
Water Solubility | 76.4 G/100 ML (30 ºC) |
Merck | 5346 |
BRN | 93773 |
BCS Class | 2 |
Cosmetics Ingredients Functions | HUMECTANT |
SKIN CONDITIONING | |
Cosmetic Ingredient Review (CIR) | Lactulose (4618-18-2) |
InChI | 1S/C12H22O11/c13-1-4-6(16)7(17)8(18)11(21-4)22-9-5(2-14)23-12(20,3-15)10(9)19/h4-11,13-20H,1-3H2/t4-,5-,6+,7+,8-,9-,10+,11+,12+/m1/s1 |
InChIKey | PFCRQPBOOFTZGQ-VZXVHDRGSA-N |
SMILES | OC[C@H]1O[C@@H](O[C@@H]2[C@@H](CO)O[C@@](O)(CO)[C@H]2O)[C@H](O)[C@@H](O)[C@H]1O |
LogP | -2.885 (est) |
CAS DataBase Reference | 4618-18-2(CAS DataBase Reference) |
EPA Substance Registry System | D-Fructose, 4-O-.beta.-D-galactopyranosyl- (4618-18-2) |
CAS Number Unlabeled | 4618-18-2 |
检测项目 Item | 指标 Standard | 检测结果Result |
外观 appearance | 白色结晶white crystal | 白色结晶 white crystal |
含量≥ content≥ | 98.0% | 99.1% |
水分%≤ Water%≤ | 30 | 20 |
比旋度 specific optical rotation | -46.0°C --- -50.0°C | -48.0°C |
灼烧残渣% ≤ ignition residue% ≤ | ≤0.2% | 0.06% |
熔点 melting point | l68°C-l73°C | l70°C |
