L-Leucine CAS 61-90-5
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L-Leucine CAS 61-90-5

L-leucine, also known as leucine, is a compound of α - amino - γ - methylvaleric acid and α - aminoisocaproic acid. Its molecular formula is C6H13O2N. Proust was first isolated from cheese in 1819, and later Braconnot obtained crystals from acid hydrolysates of muscle and wool, which were named leucine.
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  • 61-90-5

  • bosschemical

  • 61-90-5

L-Leucine Basic information
description Chemical Properties Uses toxicity
Product Name: L-Leucine
CAS: 61-90-5
MF: C6H13NO2
MW: 131.17
EINECS: 200-522-0
Mol File: 61-90-5.mol
L-Leucine Chemical Properties
Melting point >300 °C (lit.)
alpha 15.4 º (c=4, 6N HCl)
Boiling point 122-134 °C(Press: 2-3 Torr)
bulk density 300-400kg/m3
density 1,293 g/cm3
vapor pressure <1 hPa (20 °C)
refractive index 1.4630 (estimate)
FEMA 3297 | L-LEUCINE
Fp 145-148°C
storage temp. 2-8°C
solubility 1 M HCl: 50 mg/mL
form powder
pka 2.328(at 25℃)
color White to Off-white
Odor at 100.00?%. odorless
PH 5.5-6.5 (20g/l, H2O, 20℃)
biological source plant
Optical Rotation [α]20/D +15.5°, c = 2 in 6 M HCl
Water Solubility 22.4 g/L (20 C)
λmax λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05
JECFA Number 1423
Sublimation 145-148 ºC
Merck 145,451
BRN 1721722
Stability: Stability Moisture and light sensitive. Incompatible with strong oxidising agents.
Cosmetics Ingredients Functions SKIN CONDITIONING
ANTISTATIC
HAIR CONDITIONING
LogP 0.8
CAS DataBase Reference 61-90-5(CAS DataBase Reference)
NIST Chemistry Reference Leucine(61-90-5)
EPA Substance Registry System L-Leucine (61-90-5)
Item Limit Result
Specific rotation (α)020 +14.9° ~ +17.3° +15.6°
Assay 98.5% ~ 101.5% 99.52%
Sulfate 108-109° C 108.4° C
Chloride ≤ 0.5% 0.30%
Iron ≤ 50 PPM 18 PPM
Residue on ignition ≤ 0.40% 0.03%
Heavy metals ≤ 0.05% < 0.03%
Arsenic (As) ≤ 1.5 ppm < 1 ppm
Loss on drying ≤ 0.20% 0.13%
pH 5.5 - 7.0 6.1

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