Hyaluronic Acid CAS 9004-61-9
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Hyaluronic Acid CAS 9004-61-9

Hyaluronic acid is a white amorphous solid, odorless and tasteless, and hygroscopic. It is soluble in water but insoluble in organic solvents. The specific rotation of its aqueous solution is -70° to 80°. Its most prominent feature is its high viscosity. The viscosity of its solution can irreversibly decrease under the following conditions: pH value below or above 7; presence of hyaluronidase; presence of many reducing substances such as cysteine, pyrogallic acid, or heavy metal ions; (4) ultraviolet radiation, electron beam irradiation, etc.
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  • 9004-61-9

  • bosschem

  • 9004-61-9

Hyaluronic acid Basic information

Product Name:

Hyaluronic acid

CAS:

9004-61-9

MF:

C14H22NNaO11

MW:

403.31

EINECS:

232-678-0

Mol File:

9004-61-9.mol

Hyaluronic acid Chemical Properties

storage temp.

−20°C

solubility

H2O: 5 mg/mL, clear, colorless

form

Lyophilized Powder

color

White

Odor

Odorless

Optical Rotation

-70~-80

Water Solubility

Soluble in water.

Major Application

3D bioprinting

tissue engineering

(Hydrogels)

Cosmetics Ingredients Functions

SKIN CONDITIONING

ANTISTATIC

MOISTURISING

HUMECTANT

Cosmetic Ingredient Review (CIR)

Hyaluronic acid (9004-61-9)

InChIKey

MAKUBRYLFHZREJ-IUPJJCKZNA-M

SMILES

[C@@H]1(O[C@H]2[C@H](O)[C@H]([C@H](O)O[C@@H]2C(=O)[O-])O)O[C@H](CO)[C@@H](O)C[C@H]1NC(=O)C.[Na+] |&1:0,2,3,5,6,9,15,18,21,r|

LogP

-6.623 (est)

CAS DataBase Reference

9004-61-9

EPA Substance Registry System

Hyaluronic acid (9004-61-9)

Test Items

Standard

Result

Appearance

White powder

White powder

Hyaluronic Acid

≥93%

96.1%

Glucuronic acid

≥43%

46.5%

Molecular weight

(0.8—1.5) X 106

1.2 X 106

PH

6.5-8.0

6.6

Solution transmittance

99.0%

99.8%

Loss on drying

<10%

7.0%

Protein

≤0.1%

0.03%

Heavy metal

<20ppm

Complies

Bacterial counts

<100cfu/g

Complies

Mold and Yeast

<100cfu/g

Complies

Staphylococcus aureus

Negative

Complies

Chlorop seu domonas

Negative

Complies

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