Honokiol CAS 35354-74-6
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Honokiol CAS 35354-74-6

Honokiol is an isomer of magnolol, a dimer formed by the polymerization of the side chain of one phenylpropanone and the benzene nucleus of another phenylpropanone, known as a neolignan. It is found abundantly in plants of the Lauraceae family and is the effective antibacterial and anti-inflammatory component of the traditional Chinese medicine Magnolia officinalis. Honokiol and magnolol are colorless needle-like crystals, sparingly soluble in water, but readily soluble in chloroform, benzene, ethanol, and caustic alkalis. Their physicochemical constants are: magnolol, mp: 102℃, UVλmaxEtOHnm(ε): 294 (8200); and magnolol, mp: 87.5℃, UVλmaxEtOHnm(ε): 294 nm (8200).
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  • 35354-74-6

  • bosschem

  • 35354-74-6

Honokiol Basic information

Product Name:

Honokiol

CAS:

35354-74-6

MF:

C18H18O2

MW:

266.33

EINECS:

609-119-8

Mol File:

35354-74-6.mol

Honokiol Chemical Properties

Melting point

86℃

Boiling point

400.1±40.0 °C(Predicted)

density

1.107±0.06 g/cm3(Predicted)

storage temp.

2-8°C

solubility

DMSO: 36 mg/mL

pka

9.89±0.48(Predicted)

form

powder

color

White to Off-White

Merck

144,742

Stability:

Light Sensitive

Major Application

food and beverages

Cosmetics Ingredients Functions

BLEACHING

ANTIOXIDANT

SKIN CONDITIONING

InChI

InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2

InChIKey

FVYXIJYOAGAUQK-UHFFFAOYSA-N

SMILES

C1(C2=CC=C(O)C(CC=C)=C2)=CC(CC=C)=CC=C1O

LogP

4.200 (est)

CAS DataBase Reference

35354-74-6(CAS DataBase Reference)

Attribute

Specification

Results

Method

Appearance

Light yellow to white powder

Light yellow to white powder

Visual

Odor

Characteristic

Characteristic

Organoleptic

Extract method

Supercritical Fluid CO2

Complies

----

Carriers used

None

Complies

----

Magnolol + Honokiol (%)

----

99.15

HPLC

Honokiol (%)

≥98

99.15

HPLC

Magnolol (%)

----

Not detected

HPLC

Moisture (%)

≤1.0

Not detected

GB 5009.3

Ash (%)

≤1.0

Not detected

GB 5009.4

Solvent residue (%)

≤0.01

<0.01

GC

Heavy metals (as Pb) (mg/kg)

≤10

<10

GB 5009.74

Lead (mg/kg)

≤0.5

<0.5

GB 5009.75

Arsenic (mg/kg)

≤0.5

<0.5

GB 5009.76

Cadmium (mg/kg)

≤0.5

<0.5

GB 5009.15

Mercury (mg/kg)

≤0.1

<0.1

GB 5009.17

Total plate count (CFU/g)

≤1,000

<10

GB 4789.2

Yeast & Mold (CFU/g)

≤100

<10

GB 4789.15

Coliforms (MPN/g)

Absent

Not detected

GB 4789.3

Salmonella (/25g)

Absent

Not detected

GB 4789.4

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