Glycyrrhizic Acid CAS 1405-86-3

Glycyrrhizic acid is a pale yellow powder with a sweet, slightly bitter taste, containing 6%–14% glycyrrhizic acid. Pure glycyrrhizic acid is a crystalline powder with an extremely sweet taste, 200–250 times sweeter than sucrose, and the sweetness lingers for a long time. Its melting point is 212–217℃. It is readily soluble in hot water, insoluble in ether, and sparingly soluble in propylene glycol and ethanol. It is stable to heat, alkalis, and salts; precipitation will occur in the solution at pH 5.4 or below 3. The oral LD50 in mice is greater than 10 g/kg. The ADI (Advanced Individual Intake) is determined by delay (FAO/WHO, 1994).

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Model:
1405-86-3
Brand:
bosschem
Code:
1405-86-3

Product Description

Glycyrrhizic acid Basic information
Product Name:	Glycyrrhizic acid
CAS:	1405-86-3
MF:	C42H62O16
MW:	822.94
EINECS:	215-785-7
Mol File:	1405-86-3.mol
Glycyrrhizic acid Chemical Properties
Melting point	220°C (rough estimate)
alpha	D17 +46.2° (c = 1.5 in alc)
Boiling point	681.01°C (rough estimate)
density	1.1442 (rough estimate)
refractive index	61 ° (C=1.5, EtOH)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO (Slightly), Ethanol (Slightly), Methanol (Sparingly), Pyridine (Slightly)
form	Solid
pka	2.76±0.70(Predicted)
color	White to Light Yellow
Odor	at 100.00 %. mild spicy
Odor Type	spicy
Merck	144,505
Stability:	Hygroscopic
Major Application	pharmaceutical (small molecule)
Cosmetics Ingredients Functions	SKIN CONDITIONING
Cosmetics Ingredients Functions	HUMECTANT
Cosmetic Ingredient Review (CIR)	Glycyrrhizic acid (1405-86-3)
InChIKey	BXFBITNYMHAJGT-KYXJNIQISA-N
LogP	4.64
CAS DataBase Reference	1405-86-3
EPA Substance Registry System	Glycyrrhizin (1405-86-3)

Analysis 分析	Specification规格	Results 结果
Assay 含量（UV）	≥95%	98.5%
【Identification】/【鉴别】 The physical and chemical理化鉴别	Positive reaction 应呈正反应	Complies 合格
Appearance 性状	White crystalline powder	Complies 合格
Ash 灰份	≤1.0%	0.5%
Moisture 水份	≤6.0%	3.8%
Heavy metals 重金属	≤20ppm	Complies 合格
As 砷	≤2.0ppm	Complies 合格
Odor 气味	Characteristic 特殊气味	Complies 合格
Particle size 粒度	100%through 80 mesh	Complies 合格
Microbioiogical 微生物指标：
Total of bacteria 细菌总数	≤1000cfu/g	Complies 合格
Fungi 霉菌	≤100cfu/g	Complies 合格
Salmgosella 沙门氏菌	Negative 无	Complies 合格
Coli 大肠杆菌	Negative 无	Complies 合格