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| Synonyms:(R)-2-Aminobutanedioic acid (2R)-2-Aminobutanedioic acid (R)-Aminosuccinic acid D-2-Aminobutanedioic acid D-Aminosuccinic acid D-Asparaginic acid Molecular Formula:C4H7NO4 Molecular Weight: 133.1 HS Code: 2922491990 Grade:Food Grade 99.7% Hazard Class:General Cargo | |||||||||
1783-96-6
Boss Chemical
1783-96-6
D-Aspartic acid ((2R)-2-aminobutanedioic acid; HOOC-CH(NH₂)-CH₂-COOH, CAS 1783-96-6) is the D-enantiomer of the amino acid aspartic acid — a white, crystalline, optically active powder that is the mirror image of the more common L-form (CAS 56-84-8). It is a naturally occurring human metabolite and is classified as a dietary supplement ingredient, making it a key raw material for sports-nutrition and supplement formulations worldwide. As a D-amino acid it is also a valuable chiral building block for enantiomerically pure peptides and fine chemicals, and it shares the versatile amphoteric and metal-complexing chemistry of the aspartic acid family (aspartate salts such as potassium and magnesium aspartate). The D- and L-forms are identical in physical properties — melting at ≈ 270 °C with decomposition, sparingly soluble in water (≈ 4.5 g/L at 25 °C) with pKa values of 1.92 / 3.87 / 9.87 — and differ only in optical rotation. With a GHS profile reported as non-hazardous by most ECHA C&L notifications, D-aspartic acid is a mild, easy-to-handle amino acid for nutrition, synthesis and research.
Core value propositions:
● Supplement Raw Material (Core Application): dietary-supplement ingredient for sports nutrition and amino-acid formulations;
● Chiral Building Block: the D-enantiomer for enantiomerically pure peptide and fine-chemical synthesis;
● Optically Active & Well-Defined: (2R) configuration, opposite optical rotation to L-aspartic acid;
Item | Specification |
Chemical Name | D-Aspartic acid ((2R)-2-aminobutanedioic acid) |
Synonyms | D-Asp; (R)-aspartic acid; D-aminosuccinic acid |
CAS No. | 1783-96-6 (L-form: 56-84-8; DL racemic mixture also available) |
EC No. (EINECS) | 217-234-6 |
Molecular Formula | C₄H₇NO₄ (HOOC-CH(NH₂)-CH₂-COOH) |
Molecular Weight | 133.10 g/mol |
Appearance | White crystalline powder |
Solubility | Sparingly soluble in water (≈ 4.5 g/L at 25 °C); soluble in dilute acids and alkalis |
Optical Activity | Optically active — levorotatory, mirror image (opposite rotation) of L-aspartic acid |
D-Aspartic acid, HOOC-CH(NH₂)-CH₂-COOH (MW 133.10), is the (2R) enantiomer of 2-aminobutanedioic acid — a chiral amino acid whose α-carbon carries four different groups (amino, two carboxyls and hydrogen). It is the exact mirror image of L-aspartic acid (the (2S) form, CAS 56-84-8), so the two share identical physical constants — melting at ≈ 270 °C with decomposition, water solubility of ≈ 4.5 g/L at 25 °C, and dissociation constants pKₐ 1.92 (α-COOH), 3.87 (side-chain COOH) and 9.87 (ammonium) — but rotate plane-polarized light in opposite directions. Like all amino acids it is amphoteric, existing as a zwitterion in water, and its two carboxyl groups give it chelating behavior toward metal ions (aspartate salts such as potassium and magnesium aspartate). D-Aspartic acid is produced by enantioselective synthesis or by resolution of the racemic mixture, and is also a naturally occurring metabolite in the human body.
● Dietary supplement ingredient: recognized classification for sports-nutrition and amino-acid supplement raw materials.
● Defined chirality: (2R) configuration with documented optical activity.
● Chiral building block: value in enantiomerically pure peptide and fine-chemical synthesis.
● Natural metabolite: occurs in the human body; mild, biocompatible amino-acid chemistry.
● Amphoteric & chelating: zwitterionic buffering and metal-complexation (aspartate salts).
1 Dietary & Sports Nutrition — Supplement Raw Material (Core Application)
D-Aspartic acid is a classified dietary supplement ingredient used as an amino-acid raw material:
● Sports-nutrition and supplement formulations: amino-acid raw material in capsules, tablets and powders.
● Amino-acid blends: D-form amino acid for specialty formulations.
2 Chiral Building Block & Fine Chemicals
● Peptide synthesis: D-amino-acid component for enantiomerically pure peptides.
● Fine-chemical intermediates: chiral synthon for asymmetric synthesis.
3 Metal Complexation & Specialty Salts
● Aspartate salt chemistry: potassium, magnesium and other metal aspartates (chelated mineral forms).
● Chelating agent: dicarboxylate chelation toward metal ions.
● Specialty formulations: buffering and complexing amino-acid chemistry.
4 Biochemical Research & Diagnostics
● Research reagent: D-amino-acid reference standard and chiral-analysis standard.
● Metabolomics and biochemistry: naturally occurring metabolite for study applications.
● Laboratory use: chiral resolution and analytical reference material.
Packaging (customizable):
● 25 kg multi-wall paper bags with PE liner; 1,000 kg big bags; small packs on request;
● White crystalline powder — keep packaging dry and intact.
Storage:
● Store in a cool, dry, well-ventilated area; keep containers tightly closed;
● Avoid moisture and prolonged high temperature (decomposes at ≈ 270 °C);
● Keep away from strong oxidizers and incompatible acids/bases.
● Factory-direct supply: own production and sourcing capability, transparent pricing, no middleman markup.
● Stable quality: strict internal control, every batch tested (assay, optical rotation, purity, residue on ignition), COA with every shipment.
● Fast response: quotations and technical support (COA, SDS, application advice); small trial orders accepted.
D-Aspartic acid is used as an amino-acid raw material in dietary and sports-nutrition supplements (it is classified as a dietary supplement ingredient), as a chiral building block for enantiomerically pure peptides and fine chemicals, in the preparation of metal aspartate salts (potassium, magnesium aspartate), and as a research reagent and analytical standard in biochemistry.
D-Aspartic acid (CAS 1783-96-6) and L-aspartic acid (CAS 56-84-8) are mirror-image enantiomers: the D-form is (2R), the L-form is (2S). They have identical physical constants — same melting point (≈ 270 °C, decomposition), same solubility and same pKa values — and differ only in optical rotation. DL-aspartic acid is the racemic 50:50 mixture of both. Because the two enantiomers behave differently in biological and chiral systems, always specify the exact form (D, L or DL) and CAS number when ordering.
Yes, D-aspartic acid has a mild safety profile: most ECHA C&L notifications (88.9% of reports) classify it as not meeting GHS hazard criteria, with a minority reporting only mild skin/eye/respiratory irritation (H315/H319/H335). It is a naturally occurring human metabolite. Handle the powder with normal dust hygiene — gloves and eye protection — and follow the SDS.
