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| Arbutin, also known as bearberry extract, with the chemical formula C12H16O7, is a component extracted from the leaves of the bearberry plant (Arbutinus argentea). It can inhibit the activity of tyrosinase in the body, prevent the production of melanin, thereby reducing skin pigmentation, removing age spots and freckles, and also has antibacterial and anti-inflammatory effects. It is mainly used in cosmetics. | |||||||||
497-76-7
bosschem
497-76-7
Arbutin Basic information | |
Product Name: | Arbutin |
CAS: | 497-76-7 |
MF: | C12H16O7 |
MW: | 272.25 |
EINECS: | 207-850-3 |
Mol File: | 497-76-7.mol |
Arbutin Chemical Properties | |
Melting point | 195-198 °C |
alpha | -64 º (c=3) |
Boiling point | 375.31°C (rough estimate) |
density | 1.3582 (rough estimate) |
refractive index | -65.5 ° (C=4, H2O) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | H2O: 50 mg/mL hot, clear |
pka | 10.10±0.15(Predicted) |
form | Solid |
color | White |
biological source | synthetic or plant |
Optical Rotation | [α]/D -64.0±2.0°, c = 3 in H2O |
Water Solubility | 10-15 g/100 mL at 20 ºC |
Sensitive | Hygroscopic |
Merck | 14,773 |
BRN | 89673 |
Henry's Law Constant | 8.2×1013 mol/(m3Pa) at 25℃, HSDB (2015) |
Stability: | Stable. Hygroscopic - store under dry nitrogen. |
Major Application | food and beverages |
Cosmetics Ingredients Functions | ANTIOXIDANT |
SKIN CONDITIONING - MISCELLANEOUS | |
BLEACHING | |
InChI | 1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1 |
InChIKey | BJRNKVDFDLYUGJ-RMPHRYRLSA-N |
SMILES | OC[C@H]1O[C@@H](Oc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O |
LogP | -1.35 |
CAS DataBase Reference | 497-76-7(CAS DataBase Reference) |
EPA Substance Registry System | .beta.-D-Glucopyranoside, 4-hydroxyphenyl (497-76-7) |
