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| Synonyms：Methyl Beta-Cyclodextrin Methyl-β-Cyclodextrin MβCD / M-β-CD Methylated β-Cyclodextrin Formula:C54H94O35 Weight:1303.3 HS Code:3505100000 Grade:Enterprise Standards Hazard Class:General Chemical | |||||||||
128446-36-6
bosschemical
128446-36-6
ITEMS | CRITERIA | RESULTS |
Appearance | White or almost white powder;Odorless, slightly sweet;Freely soluble in water and methanol, soluble in ethanol and ethylene glycol, almost insoluble in cyclohexane and ethyl acetate. | conform |
Assay (on the dried basis) | ≥98% | 99.9% |
Specific rotation | +154°~+165° | +161° |
Water solution pH | pH5.0~7.5 | 6.2 |
Clarity of solution | 2.5g/25ml water solution is clear. | conform |
Light‑absorbing impurities | Between 230 nm and 350 nm,the absorbance is not greater than 1.0; and between 350 nm and 750 nm, the absorbance is not greater than 0.1. | conform |
Average degree of substitution | 7.0~13.3 | 12.61 |
Loss on drying | ≤7.0% | 2.8% |
Beta cyclodextrin | ≤0.2% | Not detected |
Residue on ignition | ≤0.5% | 0.09% |
Heavy metal | ≤10ppm | <10ppm |
Chloride | ≤0.2% | <0.2% |
The total aerobic microbial count | ≤1000cfu/g | <10cfu/g |
The total combined molds and yeasts count | ≤100cfu/g | <10cfu/g |
Escherichia coli | Absence | Not detected |
1.Water Soluble Cyclodextrin For Poorly Soluble Actives: Beta cyclodextrin methyl ethers (CAS 128446-36-6) are randomly methylated cyclodextrins whose substitution lifts water solubility well above unmodified beta cyclodextrin, making them effective solubilisers for poorly soluble organic compounds.
2.Inclusion Complex Formation: The methylated cavity still forms inclusion complexes with guest molecules, and the derivative is also more soluble in organic solvents, so formulation work can run in water based or solvent based media.
3.Cosmetic And Personal Care Solubilisation: In creams, gels and other aqueous systems it complexes hydrophobic molecules and brings them into the water phase, helping formulators use oil loving actives in water based products.
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